Description

ORNIBUR Intermediate

Live Attenuated Vaccine Against Infectious Bursal Disease (Gumboro)

The variable region of the genome encoding the VP2 surface antigen of infectious bursal disease virus (IBDV) was analyzed in selected vaccine strains and field isolates. A phylogenetic tree was constructed based on sequence analysis of amplified products and data retrieved from the NCBI GenBank database. The vaccine strain Bio 55: IBDV OP-23 clustered closely with the attenuated vaccine strains D-78 and Cu-1 in the phylogenetic analysis.

Key Characteristics & Efficacy

✅ Suitable for use from 7 days of age against infectious bursal disease, providing active immunization in chicks

✅ Safety studies have confirmed that the IBDV OP-23 vaccine strain is safe for the target species, and its passage through the host does not increase virulence nor induce clinical signs of disease

✅ Administration of a ten-fold overdose, using all recommended routes and methods of administration, has been demonstrated to be safe for the target species

✅ The live attenuated IBD virus induces specific immunity against Gumboro disease by stimulating the lymphoid system

Composition :

Active substances : virus bursitidis infectiosae avium min. 10^4,0 TCID₅₀ , max. 10^5,3 TCID₅₀ in one dose

Excipients : nutrimentum pro lyophilisatione

Pharmaceutical form:

Lyophilizate intended for oral and into conjuction application.

Effect method:

After vaccination, the immunity arises in one to two weeks and at broylers it lasts until the end of feeding period and at layers to the end of laying period.

The chickens in andangered flocks should be revaccinated in one to two weeks and chickens in rearing should be revaccinated again at the age of seven weeks.

Methods of immunisation:

For oral application, prepare the vaccination solution only in such volumes that can be consumed within 2 hours from the moment of its preparation. For intra-conjunctival application, apply one drop of the vaccination solution into the animal`s conjunctiva bag and let it absorbed.

Indication:

For preventive vaccination against avian infectious bursal disease (Gumboro disease).

Contraindication:

It is not recommended to vaccinate ill fowls.

Interaction:

The application of any other live vaccine is not allowed sooner than in a week. By not keeping this period, especialy with the same application method of live vaccines, the rise of immunity is limited.

Dosage:

Oral, into conjunction

Adverse effects:

Unknown

Warning:

Vaccine can be only diluted in cold drinking water, free of any desinfectants. The diluted vaccine is applied in such volumes of water, which poultry can drink within 1 to 2 hours from the moment the vaccine was diluted. Fowls should not be given any water before vaccination in order to assure quick consumption of water containing the vaccine.