Description

Linco-Sol 400 mg/g

Linco-Sol 400 mg/g powder for use in drinking water for pigs and chickens

Pharmacotherapeutic group:

lincosamide antibiotic

Active substance:

Lincomycin (as hydrochloride) 400 mg/g

Pharmaceutical form:

Powder for use in drinking water.White or almost white powder.

Target species:

Chicken (broiler)

Indications for use, specifying the target species:

Treatment of infection caused by mycoplasma and bacteria susceptible to Lincomycin for example: Pigs: swine dysentery caused by Brachyspira hyodysenteriae and mycoplasma pneumonia associated with Mycoplasma hyopneumoniae.

Chicken: necrotic enteritis caused by Clostridium perfringens

Adverse reactions (frequency and seriousness):

Lincomycin may occasionally cause transient soft stools and/or mild swelling of the anus within the first two days of treatment. Very rarely some pigs may show reddening of skin and mild irritable behavior. These conditions are usually self-correcting within 5-8 days without discontinuing Lincomycin treatment.

Dosage:

Necrotic enteritis caused by Clostridium perfringens: the daily dose is 5 mg lincomycin per kg of body weight for 7 days.

Administration:

To be administered orally, in the drinking water.

The concentration to be used depends on the actual body weight and the water consumption of the animals and can be calculated as follows:

Pharmacodynamic properties:

Lincomycin is a lincosamide antibiotic produced by Streptomyces lincolensis. Lincomycin is bacteriostatic in action inhibiting the protein synthesis predominantly by binding to the 50S ribosomal subunits of bacteria.

Depending on the sensitivity of micro-organisms, and on the concentration of the active substance the protein synthesis inhibition antibacterial action can either be bacteriostatic or bactericide.

Lincomycin is active against a wide range of Gram-positive micro-organisms, including also anaerobic bacteria such as clostridia and Brachyspira spp., as well as Mycoplasma spp.

Contraindications:

Do not use in case of hypersensitivity to the active substance or to the excipient.

Do not use if resistance to lincosamides has been detected.

Do not administer to horses, ruminants, guinea pigs, hamsters, chinchilla and rabbits. Ingestion by these species may result in severe gastrointestinal effects.

Withdrawal period(s):

Meat and offal of chicken (broiler): 5 days

Shelf life:

Shelf-life of the veterinary medicinal product as packaged for sale: 2 years

Shelf-life after first opening the immediate packaging: 3 months

Shelf-life after dilution or reconstitution according to directions: 24 hours

Nature and composition of immediate packaging:

150 g polypropylene container with polypropylene lid and inner bag of LDPE.

1.5 kg polypropylene container with polypropylene lid and inner bag of LDPE.

5 kg polypropylene container with polypropylene lid and inner bag of LDPE.

Not all pack sizes may be marketed.

by LAVET Hungary